Literature and Resources


  1. Cousins, L.M. et al. (2005) AmniSure® placental alpha microglobulin-1 rapid immunoassay versus standard diagnostic methods for detection of rupture of membranes. Am. J. Perinatol. 22, 317–20. – Read here 
  2. Lee, S.E. et al. (2007) Measurement of placental alpha-microglobulin-1 in cervicovaginal discharge to diagnose rupture of membranes. Obstet. Gynecol. 109, 634–40. – Read here  
  3. Neil and Wallace (2010) – Is AmniSure® useful in the management of women with prelabour rupture of the membranes? Australian and New Zealand Journal of Obstetrics and Gynaecology 2010; 50: 534–538. – Read here
  4. Caughey, AB.. et al. (2008) Contemporary Diagnosis and Management of Preterm Premature Rupture of Membranes. Rev. Obstet. Gynecol;1(1):11–22. – Read here 
  5. Medina, T. and Hill, D.A. (2006) Preterm Premature Rupture of Membranes: Diagnosis and Management. Am. Fam. Physician ;73(4):659-664. – Read here 
  6. Sosa, C.G. et al. (2014) – Comparison of placental alpha microglobulin-1 in vaginal fluid with intra-amniotic injection of indigo carmine for the diagnosis of rupture of membranes. DOI 10.1515/jpm-2013-0245 J. Perinat. Med. 2014; 42(5): 611–616. – Read here 
  7. Tagore, S. and Kwek, K. (2010) Comparative analysis of insulin-like growth factor binding protein-1 (IGFBP-1), placental alpha-microglobulin-1 (PAMG-1) and nitrazine test to diagnose premature rupture of membranes in pregnancy. J. Perinat. Med. 38, 609–12. – Read here 
  8. Albayrak, M., et al. (2011) Comparison of the diagnostic efficacy of the two rapid bedside immunoassays and combined clinical conventional diagnosis in prelabour rupture of membranes. Eur. J. Obstet. Gynecol. Reprod. Biol. 158, 179–82. – Read here 
  9. Ramsauer, B. et al. (2015) Effect of blood on ROM diagnosis accuracy of PAMG-1 and IGFBP-1 detecting rapid tests. J. Perinat. Med. 43, 417–22. – Read here  
  10. Ramsauer, B. et al. (2013) The diagnosis of rupture of fetal membranes (ROM): a meta-analysis. J. Perinat. Med. 41, 233–40. – Read here 
  11. Birkenmaier, A. et al. (2012Placental a-microglobulin-1 to detect uncertain rupture of membranes in a European cohort of pregnancies. Arch Gynecol Obstet. 285:21–25 DOI 10.1007/s00404-011-1895-9.- Read here 

Other useful links

  • NICE Guidelines 25 – Read here 
  • Greentop Guidelines no. 73 – Read here 
  • European Guidelines for the management of spontaneous preterm labour, 2011. – Read here  

Clinical Literature and Resources

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