Available on NHSSC
The only rapid, non-invasive PROM test that compares to the gold standard.
What is AmniSure®?
How does it work?
AmniSure® is a point-of-care one-step immunochromatographic assay which detects the placental alpha microglobulin-1 protein (PAMG-1) using specific monoclonal antibodies. AmniSure has been evaluated in more than 20 peer reviewed clinical studies and has been found to have a sensitivity of 98.9% and specificity of 100% 1.
With intact membranes, the background concentration of PAMG-1 in vaginal discharge is 0.05-0.22 ng/ml 2. PAMG-1 concentration is much higher in amniotic fluid (2,000-25,000 ng/ml) 1 regardless of gestational age. Therefore, any leakage of amniotic fluid due to a rupture will significantly increase the vaginal PAMG-1 concentrations. AmniSure has a sensitive threshold of 5 ng/ml, enabling the detection of even a miniscule amount of amniotic fluid leakage.
The risks of untreated PROM and the cost of an unnecessary admission are significant, and studies have found clinicians may be uncertain on PROM diagnosis in 47% of cases 3.
AmniSure’s proven reliable accuracy gives you confidence in your diagnosis, enabling timely and appropriate care with peace of mind.
The simple 4-step procedure gives a clear result within minutes.
Key Benefits
Highest Accuracy
Cost Effective
Enhanced Safety and Risk Management
Easy to Use
Painless
AmniSure® vs ActimPROM:
Performance metrics in patients with unknown membrane status and vaginal bleeding 7
Literature and Resources
FAQs
Will lubricant gel effect the outcome of the test?
Which gestation can the test be used on?
Can AmniSure be used if blood is present?
Does a faint line on the AmniSure test strip mean positive or negative?
Does the swab need to be rotated in the vagina?
Order today on NHS Supply Chain
Or order direct via AGHealth.
Your dedicated account manager will provide personalised support tailored to your hospital’s needs and protocols.
Complete the contact form to request pricing, order information, book a meeting, or trial AmniSure for free in your hospital.